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S2CID 39735609
Outcome measures histological scoring and gross visual assessment are not functional outcomes
However, serious adverse effects can occur, including pancreatitis (severe persistent abdominal pain), gallbladder disease, and acute kidney injury (typically related to dehydration from gastrointestinal symptoms)
Administration of sesamin prior to MPTP exposure significantly reduced oxidative stress in the mouse brain: it suppressed the production of ROS and prevented the induction of iNOS and IL-6 in activated microglial cells (66)
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