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This decision followed a comprehensive FDA review that found no increased risk of suicidal thoughts or behaviors associated with GLP-1 use

Anecdotal evidence suggests significant changes in body composition become apparent within this timeframe

Major complications included hyperbilirubinemia (44.8%), ALT elevation (34.5%), liver failure (14.2%), infection (2.1%), cerebral haemorrhage (0.04%), and hematuria (0.04%)

It acts by mimicking the endogenous hormone ghrelin and binding to the growth hormone secretagogue receptor type 1a (GHS-R1a) in the anterior pituitary gland

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