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In dermal fibroblasts cultured from aged donors, GHK-Cu treatment (2 M) increases TIMP-1 mRNA expression by approximately 25%, contributing to reduced net collagenolytic activity and preservation of existing matrix structures

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Interestingly, the female steady-state is low for S near 1 and also low for S = 3.31, but at intermediate values of S , the female steady-state is considerably higher than that the male's

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