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Effect of hyperammonemia on the levels of carnitine in mice

Clinical trials show average weight loss ranging from around 16% to over 22% of body weight over roughly a year and a half, depending on dose and adherence

In this context, the data currently available on tirzepatide, showing its efficacy in glycemic control to the extent that a considerable percentage of patients achieve glucose levels indicative of diabetes remission [3, 59], as well as its high effectiveness in weight management, are promising regarding its future use in clinical practice