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n=17), compared to the ~0.4% increase in HbA1c seen post-GLP-1 discontinuation in the STEP-1 trial extension 2 of GLP-1 withdrawal

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After 56 weeks: Placebo group lost 1.6% of body weight Starting dose (3.75/23 mg) group lost 5.1% of body weight Top dose (15/92 mg) group lost 10.9% of body weight Beyond weight loss, the CONQUER trial showed significant improvements in blood pressure, waist circumference, lipid profiles, glycemic parameters, and inflammatory biomarkers compared to placebo

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For those with type 2 diabetes, Semaglutide can also help reduce the risk of cardiovascular events

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LIRA KO by 2-factor ANOVA

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Key safety information in the Prescribing Information includes: Use in patients with prior pancreatitis: Tirzepatide has not been studied in patients with a history of pancreatitis

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