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The second mechanism by which glutathione causes lightening of skin is inhibition of transfer of tyrosinase to premelanosomes for melanin synthesis.[] The third mechanism of tyrosinase inhibition is through its antioxidant effect as it scavenges the free radicals generated in the epidermis following UV light irradiation

Conflicts of interest The authors of this manuscript have no relationship or financial interests with companies related to the findings of the study

Proper positioning on the toiletwith feet elevated on a small stool to create a squatting posturecan facilitate easier evacuation