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Affecting over 25% of American adults and 25%30% of the global population, this multimorbidity comprises five stages with escalating mortality risk: stages 01 (metabolic dysfunction without significant target organ impairment), stages 23 (early cardiovascular and kidney injury), and stage 4 (severe cardiovascular events or kidney failure) ( For this review, we searched PubMed, Embase, Web of Science, Cochrane Library, CNKI, and Wanfang Data up from January 2010 to December 2025
Medicinal chemistry strategies for the development of phosphodiesterase 10A (PDE10A) inhibitors - an update of recent progress
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Nitrate and gastric cancer risks
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