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The American College of Rheumatology guidelines emphasize weight loss as a core non-pharmacological intervention for overweight and obese patients with knee osteoarthritis, with evidence supporting that even modest weight reduction (5-10% of body weight) can produce clinically meaningful improvements in pain and function
Skin collagen synthesis Hair, skin, and nail health Energy and nervous system support Bone health, immune support, mood enhancement Immune boost, antioxidant, collagen production Inflammation, pain, decrease leukocytosis
PMC 8012690
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