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Gastrointestinal adverse events were mostly mild or moderate, with no severe diarrhea reported and only one instance of severe nausea or vomiting in any dose group

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Change history 19 March 2025 The original online version of this article was revised: "The designation of co-first authorship was clearly stated in our submitted and revised versions, but it is missing in the published article

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Primary brain tumors arise from intracranial elements such as the cerebral hemispheres, the base of the skull, the hypothalamus, the basal ganglia, the thalamus, the brainstem, and the cerebellum