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A randomized, placebo-controlled pilot study examined adding phentermine to liraglutide (a GLP-1 agonist similar in class to tirzepatide) in adults with obesity who had already been on liraglutide for one year and achieved approximately 12% weight loss
However, the landscape has changed
194 The pathophysiology is thought to involve ischemia due to microangiopathy and metabolic disturbances
Medical science now better understands and explains the critical role that hormones play in weight management and metabolism (the processing, storage, and utilization of calories for energy)
More significant weight loss typically occurs after 12 to 16 weeks of consistent use
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