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Uremia symptoms can vary considerably and might include feeling sick, throwing up, feeling tired, losing appetite, losing weight, having a foul taste in the mouth, and experiencing changes in mental status, like confusion or memory loss
It also supports a healthy metabolism, endurance, and recovery
Histidine persists in its neutral form between the pH of 6.00 (equivalent to pK a 3 for the side chain pyrrole NH group, which corresponds to the equilibrium between the positive and neutral form) and pH 9.17 (equivalent to pK a 2 of the amino group which corresponds to the equilibrium between the negative and neutral forms)
References Global Burden of Disease Network (2021) Global burden of disease study 2021 (GBD 2021) Results
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