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Off-label use risks Many peptides are not FDA-approved for general therapeutic use and should only be prescribed by licensed medical professionals

Gels were cast homemade using Acrylamide/bisacrylamide (Fisher Bioreagent), APS (Biosolve), TEMED (Sigma) and Tris-glycine buffer

So while it is technically \u201coff-label\u201d to inject other parts of the face, we consider this to be a safe use of this product because it is so similar to a handful of other hyaluronic acid fillers which have been used for years to inject throughout the face