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Cycling is recommended

Adverse side effects are possible

For UK patients in 2025, switching between these medications requires careful planning and support

"Nobody's minding the store," said Stuart Phillips, a professor of kinesiology at McMaster University in Hamilton

Secondary outcomes The secondary outcomes are as follows: type 2 diabetes, glucose, HbA1c, insulin, lipid profile (LDL-cholesterol, HDL-cholesterol, triglycerides and apolipoprotein B), systolic blood pressure, diastolic blood pressure, and body mass index (BMI), which are well-established risk factors for CVD in clinical practice, or recently identified to be related to CVD in MR, such as apolipoprotein B [30, 31]