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Yesin a study published in Endocrine Practice, people who switched directly from a GLP-1 treatment (including semaglutide) to tirzepatide at 5 mg saw improved blood sugar control and additional weight loss within 12 weeks, with milder digestive side effects that typically seen in patients starting tirzepatide for the first time
Overdosage In the event of overdose with JANUMET XR, contact the Poison Control Center
Masterton GS, Plevris JN, Hayes PC
The Salehpour 2019 study (80 women, 3,000 mg/day, 12 weeks) reported no relevant side effects
"It could also be the case that the underlying indication, for example, which is obesity, is also known to have a higher risk for mental health issues," he says
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