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Additional ubiquitin molecules are conjugated onto the first, forming a polyubiquitinated adduct that is recognized by the 26S proteasome leading to substrate degradation (Figure 1

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[5] Peptides such as AOD 9604 and retatrutide, when sold with implied therapeutic claims (e.g., fat loss, metabolic enhancement), may legally constitute unlicensed medicinal products, regardless of how they are labelled by suppliers

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