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The results were uploaded to a pathway mapping platform ( to identify the activated pathways

In vivo, ouabain-treated mice harbored a decrease of senescent cells in an OIS model, a whole-body irradiation model as well as in aged mice

Some researchers suggest that it inhibits an enzyme variant related to COX-2 in the brain, which produces pain and inflammation signaling molecules, thus reducing pain sensation

2004 Jul;11 Suppl 1:S73-85

Moreover, in both infected and mock-infected cells treated with inhibitor, levels of NRF2 and G6PD proteins ( Figure 6B ), as well as intracellular GSH/GSSG ratio ( Figure 6C ), increased in comparison to untreated cells