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10.1002/mas.21381 Mass Spectrometry Rev
It does not increase growth hormone levels
Other natural compounds with evidence for stimulating GLP-1 include curcumin from turmeric, which activates similar metabolic pathways, green tea catechins that influence incretin hormone production, and specific amino acid combinations that trigger L-cell signaling
The use of GLP-1 RAs for these conditions is still off-label , and the literature lacks clear guidelines on the appropriate drug management in these clinical uses [8]
Interestingly, only a very small amount of GLP-1R is present in the -cell membrane, but GLP-1 can inhibit glucagon secretion in human pancreatic islets by directly acting on GLP-1R on -cells
