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Lixisenatide and twice-daily exenatide were compared in the GetGoal-X trial, which found that lixisenatide was not inferior to exenatide in lowering HbA1c ( 0.79% vs
Differences in the composition of the amino acid sequence between the porcine and human peptide could also have affected their biological activity, in particular the degree to which they activated the release of insulin
It is specifically formulated and approved for injection into the fatty tissue beneath the skin, not for intravenous use
Se ha estimado que del 50 al 70% de la respuesta de la insulina a la ingesta de la glucosa oral es atribuible al sistema incretnico16
These side effects occurred more frequently than in previous phase III trials, a finding that the authors attribute to the enforced dose escalation scheme
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