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In contrast to earlier GLP-1 receptor agonists, which primarily target appetite suppression and glycemic improvement, GLP-3 leverages GCG receptor activation to stimulate lipolysis and elevate basal metabolic rate, thereby contributing to a more pronounced and sustained reduction in adiposity as observed in research models
Trends Mol Med 2015
The Nrf2 protein then translocates into the cell nucleus, where it binds to the Antioxidant Response Element (ARE) on the DNA
M.GullnerG.KirlyZ
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