is tirzepatide and glp 1 the same GLP-1 vs. GLP-1 + GIP: What's Difference for your Metabolism? Retatrutide vs Semaglutide and Tirzepatide:

PMCID: PMC10385428

10.1038/s41430-024-01460-6 4 AvogaroA.FadiniG

Clinical Considerations and Safety Clinical trials of Retatrutide have generated significant excitement in the medical community due to its exceptional efficacy in treating obesity and metabolic dysfunction

127 Hypoxia and metabolic reprogramming within the TME additionally impair T-cell infiltration and function, reinforcing an immunologically cold phenotype

Summary: GLP-1 receptor agonists are not licensed for NAFLD treatment in the UK but may reduce liver fat and improve metabolic parameters when prescribed for type 2 diabetes or weight management in eligible patients with concurrent liver disease