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Here, our genetic screening of the previously constructed hairpin RNA-based Arabidopsis library identifies a glutathione (GSH)-deficient mutant that has high accumulation of glutamate (Glu), a previously defined wound signal essential for activating plant defense, but disharmoniously exhibits attenuation of defense signaling events

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This structural modification documented in a 2020 Endocrine Reviews study enhances the peptides stability against dipeptidyl peptidase IV (DPP-IV) degradation, extending its half-life and producing a more sustained GH-releasing effect

& Tzvetkov, M

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