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As isolated as an air-stable solid and available commercially, cobalt in vitamin B 12 (cyanocobalamin and other vitamers) is present in its +3 oxidation state
Chem Soc Rev 42(16):66206633
Selective pretreatment of endothelial cells with methylene blue before co-culture with untreated rabbit pulmonary arterial smooth muscle produced a reduction in rabbit pulmonary arterial smooth muscle cyclic guanosine monophosphate levels of a magnitude comparable with that seen in cocultures of methylene blue pretreated rabbit pulmonary arterial smooth muscle with untreated endothelial cells, and which was partially prevented by superoxide dismutase
In StatPearls.
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