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Sleep is typically assessed using polysomnography and actigraphy to provide objective sleep data and questionnaires to provide subjective information
A confirmatory analysis also showed that 33% of patients in the semaglutide group achieved both endpoints (resolution of steatohepatitis and improvement in fibrosis) compared with 16% of those receiving placebo
Allow 2-4 weeks at each new dose to assess response before further adjustment
GLP-1 receptor agonists have been administered as subcutaneous injections
doi: 10.2337/db10-0328 33 BergmanBCHowardDSchauerIEMaahsDMSnell-BergeonJKEckelRHet al
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