Storage Lyophilizate (dry powder before reconstitution) 2 years at 20 C (freezer) 18 months at 2 to 8 C (refrigerator) Up to 30 days at room temperature (up to 25 C), protect from light and moisture After reconstitution (peptide in solution with bacteriostatic water) Up to 30 days at 2 to 8 C , protected from light The cyclic structure makes Melanotan II relatively stable in solution, more stable than most linear peptides Practical storage rules Allow the vial to warm to room temperature (15 to 20 min) before opening
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Dosing generally starts at 2 mg per week and is increased gradually over several weeks to 4 mg, 8 mg, or 12 mg
Timing of Administration While retatrutide is administered weekly via subcutaneous injection, some researchers report that timing the injection relative to meals can influence GI symptom severity