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Side effect profile differences that affect conversion strategy Semaglutide and tirzepatide share a common GLP-1-mediated side effect profile (nausea, vomiting, diarrhea, constipation, gastroparesis), but the GIP receptor component of tirzepatide changes the relative frequency and severity of specific effects

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OASIS 1 met its primary endpoint of a statistically significant weight loss at week 68 in the oral semaglutide (50 mg) versus placebo group, whihch marks a milestone step toward the goal of an oral weight loss drug

Severe Constipation Constipation and GLP 1 medications frequently go hand in hand

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