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We propose that dysbiosis promotes ferroptosis in ovarian granulosa cells through disrupted iron homeostasis, diminished production of protective microbial metabolites, and systemic inflammation, collectively contributing to the reproductive and metabolic disturbances in PCOS
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[6], [7] The ghrelin receptor is overexpressed in various conditions like human carcinoma and heart failure, making it a potential target for disease diagnosis and staging
Through the fine-tuned modulation of autophagic flux, astrocytes maintain cellular homeostasis and contribute to neuronal protection under disease conditions
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