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DPP-4 inhibition increases intact and active GLP-1 (and GIP) levels after a meal and the levels remain elevated until the next meal
This is often attributed to an increase in time spent in REM sleep, which is the stage of sleep where most dreaming occurs and cognitive recovery happens
Record it but do not react to single data points
We excluded 40 individuals who were already using insulin, 44 who started insulin therapy after discontinuing GLP-1 receptor agonists, and 70 with missing baseline or follow-up HbA1c values
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