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Unlike small-molecule drugs that may remain stable at room temperature, peptide medications are sensitive to environmental factors including temperature fluctuations, light exposure, and physical agitation

The IGF-1 axis benefits from the same pause: it drifts back toward baseline instead of sitting chronically elevated, which is the safer position given GH/IGF-1s growth-promoting signaling

For others, having three structured meals works best to align with their body's natural hunger cues, which are already being influenced by the GLP-1 medication

In: Simpson, Kathleen Rice, Creehan, Patricia A