One posited mechanism is the activation of phospholipase C (PLC), which, according to some researchers, might subsequently facilitate the release of inositol triphosphate (IP3) and diacylglycerol (DAG)
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Standardization of measurement techniques, reporting of important patient characteristics such as disease severity, onset, and duration, as well as concomitant illnesses and medications, and additional studies in MCI would allow for better characterization of early biomarkers changes in different stages of cognitive impairment
NAD is a coenzyme that supports mitochondrial energy production, cognitive function, and DNA repair