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Initial evaluation of whitening properties in vitro should be conducted on purified TYR and/or other melanogenic proteins, followed by the use of melanocyte cultures to examine potential cytotoxic and melanin synthetic effects

In 22 24-month-old mice given 10 mg/kg once daily for 8 weeks, sedentary animals gained roughly 40% grip strength over controls, and animals that also exercised gained about 60%

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To further verify the role of AMPK on MG-induced beta cell apoptosis, we pre-treated cells with 10 M compound C (a selective AMPK inhibitor) in MG-treated INS-1 and MIN6 cells