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There are a few GLP-1s being marketed exclusively as anti-obesity medications
Until robust phase III clinical trial data becomes available comparing transdermal and injectable GLP-1 formulations directly, healthcare professionals must rely on established injectable therapies with proven efficacy and safety profiles for managing type 2 diabetes and obesity
They improve insulin signaling within weeks, even in people without diabetes, which reduces the livers overproduction of triglycerides and allows muscle tissue to recover insulin receptor function
2013, 108 (4): 365-10.1007/s00395-013-0365-x
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