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New England Journal of Medicine, 384(11), 989-1002
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Preclinical studies suggest ALA may help defend neurons against oxidative stress, support synaptic function, and maintain healthy levels of glutathione, a critical antioxidant in brain cells.12 25 Importantly, ALA can cross the blood-brain barrier, making it a promising candidate for addressing conditions where oxidative stress or mitochondrial dysfunction play a role
Ticinesi A, Maggi S, Nouvenne A, Zuliani G, Franceschi C
However, there are to date no clinical studies that have examined neuroprotective effects of neither endogenous nor pharmacologically administered GLP-1 in mitigating the impact of a stroke in humans [20]
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