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Because cobalamin in normally absorbed from food through the gastrointestinal tract, chronic diseases that adversely affect the ability of the intestines to absorb nutrients (inflammatory bowel disease is an excellent example) can lead to cobalamin deficiency

Synthesis Synthesis of Glutathione(GSH) occurs via a two-step ATP-requiring enzymatic process

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More specifically, overexpression of insoluble A may drive alterations in gamma oscillations and glutamatergic gene expression in the prefrontal cortex, potentially underlying changes in anxiety-related behaviors (Pervolaraki et al., 2019)

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