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A subsequent scRNA-seq study on human islets documented a similar alpha-cell subpopulation consisting of a small number of proliferating alpha-cells, expressing TOPA1 , CENPF , and AURKB (72)
Some patients need dose adjustments, side effect management, protein support, strength training guidance, or a broader evaluation of hormonal and metabolic factors
These disparities may be related to differences in cell type (salivary gland versus lymphocyte) or readouts (glutathione/senescence versus viability)
Lombardi, S
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