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Tirzepatide (MOUNJARO) Pronounced: tir ZEP a tide / mown JAHR OH Mnemonic: Tear zeppelin (over) Mount (Kiliman)jaro Year of release: 2022 Cost: $1060 / mo FDA-approved for: Type 2 diabetes Mechanism: dual GLP-1/GIP receptor agonist Available doses: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg (weekly subcutaneous injection) Dynamic interactions: Glucose lowering Kinetic interactions: Delayed gastric emptying, otherwise none significant in a bubble Tirzepatide (Mounjaro) is the first twincretin for type 2 diabetes

Obesity is implicated in the development of cardiometabolic complications including type 2 diabetes (T2DM), coronary heart disease, non-alcoholic fatty liver disease and certain cancers [2, 3]

Mechanisms of anti-inflammatory and neuroprotective actions of PPAR-gamma agonists

GLP-1 Medicare coverage refers to Medicare reimbursement for qualifying GLP-1 medications prescribed for approved medical conditions such as type 2 diabetes and certain cardiovascular indications

Glapp Best for medication-cycle interpretation 4.9 (505 App Store ratings) iPhone Web browser Glapp reads like an analyst for your dose curve: shot phases, rise-peak-fade explanations of estimated levels, and supply tracking for vials and pens with concentrations and beyond-use dates