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Mental health GLP-1 medications have been under regulatory review for possible links to suicidal thoughts and mood changes

Lilly is studying retatrutide in several Phase 3 clinical trials to evaluate its potential efficacy and safety in obesity and type-2 diabetes, along with other adjacent comorbidities including knee osteoarthritis pain, moderate-to-severe OSA, chronic low back pain, metabolic dysfunction-associated steatotic liver disease and several others.

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