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International Organization for Standardization

While these findings are encouraging, several considerations warrant attention: Because GHK-Cu contains copper, following usage directions carefully helps prevent potential copper toxicity

The honest summary is that the country may soon get a cleaner supply of compounds nobody can say much about yet.

Its activity intersects two major metabolic pathways simultaneously: the NAD+ biosynthesis pathway (by consuming nicotinamide, an NAD+ precursor, NNMT competes with the NAD+ salvage pathway) and the methyl-donor pathway (by consuming SAM, NNMT reduces the availability of methyl groups for epigenetic and metabolic methylation reactions)

Chang J 1 , Leong RW 2 , Wasinger VC3, Ip M4, Yang M4, Phan TG5