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Here, we demonstrated that preferential accumulation of peroxidized phospholipids and loss of the antioxidant enzyme glutathione peroxidase 4 (GPX4) were responsible for vulnerability of midbrain dopaminergic neurons and progressive motor dysfunctions in a mouse model of PD

10.1053/j.gastro.2014.07.046 50

doi: 10.1016/j.prmcm.2023.100264 172 HamayaSOuraKMorishitaAMasakiT

Nguyen T, Nioi P, Pickett CB