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PubMed research supports that insulin resistance is a core factor in various health issues beyond diabetes, including fatty liver, cognitive impairment, and cardiovascular disease (Springer)
However, it can interact with a number of other medications, potentially leading to serious side effects
Nauck MA, Meier JJ, Cavender MA et al (2017) Cardiovascular actions and clinical outcomes with glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors
When patients attempt to exert themselves physically, cognitively, or even emotionally, their damaged, inefficient mitochondria simply cannot meet the sudden energy demand
36 The next frontier: Quality weight loss The current generation of GLP-1s is fantastic at dropping weight, but a strategic vulnerability is muscle wasting. Up to 25-40% of the weight lost on these drugs can be lean muscle mass
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