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Ironically, a side effect of excessive anticholinesterase treatment is excessive weakness or cholinergic crisis due to excessive stimulation of nicotinic receptors in the muscle end-plate region, resulting in a transient phase of uncontrolled muscle fasciculations due to sustained depolarization, followed by the development of receptor desensitization and a flaccid paralysis

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Activit physique modre : marches dynamiques, un peu de renforcement musculaire, danse sans tomber dans lexcs de sport intensif sans rcupration