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Previous AngIV analogs, while showing promise in animal models of dementia, were hindered by poor metabolic stability indicated by a short half-life, and an inability to cross the BBB due to their peptide nature
Given the relatively older population (median age 69 years), non-cardiovascular mortality over the 4.5-year follow-up period may reduce the number of individuals at risk for cardiovascular events, potentially leading to modest overestimation of projected event rates
This effect decreases over time, however the action of sending the "I'm full" signal is why Semaglutide works over long periods of time
Liquid lasts weeks
Stay tuned to my blog and Resiliency Radio podcast for updates on this evolving story
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