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Diabetes Metab Syndr Obes 2017;10:123139.ArticlePubMedPMC 94

The American Diabetes Association recommends that adults with type 2 diabetes undergo comprehensive dilated eye examinations by an ophthalmologist or optometrist at the time of diabetes diagnosis

Because Melanotan stimulates pigment-producing cells, case reports have documented darkening of existing moles and the appearance of new pigmented lesions in people using it, along with reports of melanoma diagnosed in users

These effects are dose-dependent and typically improve during the first 4 to 8 weeks of treatment